Title | Postcoital penile washing and the risk of HIV acquisition in uncircumcised men |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Makumbi, FE, Ssempijja, V, Sekasanvu, J, Ssekubugu, R, Kigozi, G, Watya, S, Nakigozi, G, Serwadda, D, Wawer, M, Gray, RH |
Journal | AIDS |
Volume | 30 |
Pagination | 1669-73 |
Date Published | Jun 19 |
ISBN Number | 1473-5571 (Electronic)0269-9370 (Linking) |
Accession Number | 27243775 |
Abstract | BACKGROUND: Postcoital genital washing by uncircumcised men may affect the risk of male HIV acquisition. METHOD: We assessed the association between self-reported washing after sex in 2976 initially HIV-negative, uncircumcised men enrolled in a prospective cohort study in Rakai, Uganda. RESULTS: Data from the 2976 participants who reported sexual intercourse in the past 12 months contributed 4290 visits, with 7316.6 person-years of observation during the 2-year follow-up. The overall HIV-incidence was 1.28/100 person-years 95%CI (1.04-1.57). About 91.0% of men reported washing their penis after sex, and their HIV incidence was 1.34/100 person-years (95%CI 1.08-1.66), compared with an incidence of 0.62/100 person-years (95%CI 0.17-1.60) in men who did not wash their penis after intercourse. Using Poisson multivariable regression, the adjusted incidence rate ratio of HIV acquisition associated with postcoital washing was 1.94 (95%CI 0.71-5.29). CONCLUSION: Postcoital penile washing, as practiced in this rural African population does not afford protection from HIV acquisition among uncircumcised men, and may increase risk. |