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Poverty and InequalitySexual and Reproductive HealthFamily, Maternal & Child HealthMethodology

Marriage and the risk of incident HIV infection in Rakai, Uganda

TitleMarriage and the risk of incident HIV infection in Rakai, Uganda
Publication TypeJournal Article
Year of Publication2014
AuthorsNalugoda, F, Guwatudde, D, Bwaninka, JB, Makumbi, FE, Lutalo, T, Kagaayi, J, Sewankambo, NK, Kigozi, G, Serwadda, DM, Kong, X, Wawer, MJ, Wabwire-Mangen, F, Gray, RH
JournalJournal of Acquired Immune Deficiency Syndromes (1999)
Volume65
Pagination91-8
Date PublishedJan 1
ISBN Number1525-4135
Accession Number24419066
KeywordsAdolescent, Adult, Female, HIV Infections/*epidemiology, Humans, Incidence, Male, Marriage/*statistics & numerical data, Middle Aged, Risk Factors, Sex Factors, Sexual and Reproductive Health, Sexual Behavior/statistics & numerical data, Sexual Partners, Uganda/epidemiology, Young Adult
Abstract

OBJECTIVE: Studies suggest that the prevalence of HIV is higher among long-term marital/consensual relationships than in the unmarried. We assessed the risk of incident HIV infection by marital status in rural Rakai, Uganda. DESIGN: Longitudinal data from the Rakai Community Cohort Study between 1999 and 2011. METHODS: We estimated HIV incidence per 100 person years (py) in sexually active individuals aged 15-49 years with a total of 44,179.6 py who were never married (women 2929 py and men 4261 py), currently married or in long-term consensual relationships (currently married women 29,823 py and men 21,299 py) and previously married (women 3563 py and men 1475). Poisson multivariable regression was used to estimate the unadjusted and adjusted incidence rate ratios (IRRs) and 95% confidence intervals (CIs) of HIV acquisition. RESULTS: The HIV incidence among currently married persons was 0.93/100 py, which was lower than that for the never-married (1.51/100 py) and previously married (2.85/100 py) persons. The risk of HIV acquisition was significantly lower in the currently married compared with that in the never married among women (Adj IRR = 0.26, 95% CI: 0.16 to 0.42), but not among men (Adj IRR = 0.69, 95% CI: 0.31 to 1.52). HIV incidence was lower among first marriages (0.73/100 py) compared with that among second- or higher-order marriages (1.38/100 py). Multiple sex partners significantly increased the risk of HIV acquisition in both women (Adj IRR = 2.53, 95% CI: 1.6 to 3.97) and men (Adj IRR = 1.77, 95% CI: 1.20 to 2.60). CONCLUSIONS: Current marriage especially first-order marriage was associated with a reduced risk of HIV acquisition in women, but not in men, and multiple sex partnerships increased HIV risk for both sexes.

PMCID

Pmc3897786