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Poverty and InequalitySexual and Reproductive HealthFamily, Maternal & Child HealthComputational Population & Health SciencesMethodology

The Association Between Lipoproteins, Disability, and Physical Function Among Older Costa Rican Adults

TitleThe Association Between Lipoproteins, Disability, and Physical Function Among Older Costa Rican Adults
Publication TypeJournal Article
Year of Publication2017
AuthorsChanti-Ketterl, M, Gamaldo, A, Andel, R, Thorpe, R. J., J
JournalJ Aging Health
Pagination898264317690866
Date PublishedFeb 01
ISBN Number0898-2643
Accession Number28553801
Keywordsbiomarkers, Frailty, Hispanics, Latin America
Abstract

OBJECTIVE: To examine the relationship between total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) with disability and physical performance. METHOD: Wave 1 data were from Costa Rican Longevity and Healthy Aging Study ( n = 2,827). Lipoprotein profiles were measured using blood samples. Disability and physical functioning were measured with activities of daily living/instrumental activities of daily living (ADLs/IADLs) and objective assessment of physical performance. RESULTS: Lower HDL-C was associated with greater ADL disability, and lower TC with longer time to pick-a-pencil and Time-Up-Go (TUG) test. Age interacted between (a) TG and lung function, chair stands, and pick-a-pencil, and (b) HDL-C and TUG. Stratification showed lower TG and longer time picking up a pencil only for those above 84 years. Based on significant interactions with sex, lower TC was associated with slower chair stand time in women and higher HDL-C with slower chair stand time in men. DISCUSSION: Lower levels of lipoproteins may suggest worse physical function, but the association may differ by sex.